|
No. of Patients (%)
| |
---|
|
Grade 1
|
Grade 2
|
Grade 3
|
Grade 4
|
---|
Hematologic event
| | | | |
Neutropenia
|
2 (7.4)
|
3 (11.1)
|
2 (7.4)
|
0 (0.0)
|
Febrile neutropenia
|
-
|
-
|
0 (0.0)
|
0 (0.0)
|
Thrombocytopenia
|
12 (44.4)
|
1 (3.7)
|
3 (11.1)
|
0 (0.0)
|
Anemia
|
10 (37.0)
|
5 (18.5)
|
2 (7.4)
|
0 (0.0)
|
Nonhematologic event
| | | | |
Asthenia
|
7 (25.9)
|
11 (40.7)
|
4 (14.8)
|
0 (0.0)
|
Nausea/Vomiting
|
10 (37.0)
|
6 (22.2)
|
0 (0.0)
|
0 (0.0)
|
Mucitis
|
3 (11.1)
|
0 (0.0)
|
0 (0.0)
|
0 (0.0)
|
Diarrhea
|
6 (22.2)
|
4 (14.8)
|
0 (0.0)
|
0 (0.0)
|
Sensory neuropathy
|
10 (37.0)
|
2 (7.4)
|
2 (7.4)
|
0 (0.0)
|
- Toxicities were evaluated according to National Cancer Institute Common Terminology Criteria for Adverse Events (version 3.0).