MiR-98 and miR-222 expression in MCF-7aro cells treated with aspirin and celecoxib. Cells are treated with androstenedione and celecoxib, and androstenedione and aspirin. Total mRNA was extracted from cells and miRNA expression of miR-98 and 222 was quantified by real-time PCR. MiR-222 expression of celecoxib and aspirin are shown in A &B, while C &D are the miR-98 expression of celecoxib and aspirin, respectively. Values are means ± SEM, n = 3. The data was analyzed by One-way ANOVA, followed by Tukey’s Multiple Comparison test when P<0.05. Means labeled with different letters are significantly different (order: c>b>a).