Table 1 Clinical characteristics of 5-year survivors of acute lymphoblastic leukemia
ALL survivors | Chemotherapy only | CRT | TBI | |||||
|---|---|---|---|---|---|---|---|---|
n = 213 | % | n = 104 | % | n = 95 | % | n = 14 | % | |
Age at diagnosis | ||||||||
<5 yrs | 111 | 52.1 | 61 | 58.7 | 45 | 47.4 | 5 | 35.7 |
5-9 yrs | 71 | 33.3 | 34 | 32.7 | 33 | 34.7 | 4 | 28.6 |
10-17 yrs | 31 | 14.6 | 9 | 8.7 | 17 | 17.9 | 5 | 35.7 |
Period of diagnosis | ||||||||
1970-1979 | 42 | 19.7 | 3 | 2.9 | 39 | 41.1 | 0 | 0 |
1980-1989 | 78 | 36.6 | 39 | 37.5 | 32 | 33.7 | 7 | 50.0 |
1990-1999 | 93 | 43.7 | 62 | 59.6 | 24 | 25.3 | 7 | 50.0 |
Age at end of follow-up | ||||||||
10-19 yrs | 54 | 25.4 | 46 | 44.2 | 6 | 6.3 | 2 | 14.3 |
20-29 yrs | 71 | 33.3 | 39 | 37.5 | 26 | 27.4 | 6 | 42.9 |
30-39 yrs | 73 | 34.3 | 15 | 14.4 | 53 | 55.8 | 5 | 35.7 |
>40 yrs | 15 | 7.6 | 4 | 3.8 | 10 | 10.5 | 1 | 7.1 |
Relapse | 24 | 11.3 | 2 | 1.9 | 11 | 11.6 | 11 | 78.6 |
Stem cell transplantation | 14 | 6.6 | 0 | 0 | 0 | 0 | 14 | 100.0 |
Cranial irradiation | ||||||||
12-15 Gy | 2 | 0.9 | 2 | 2.1 | 0 | 0 | ||
18 Gy | 28 | 13.1 | 28 | 28.4 | 1 | 7.1 | ||
20-23 Gy | 6 | 2.8 | 6 | 6.3 | 0 | 0 | ||
24-30 Gy | 62 | 29.1 | 60 | 63.2 | 2 | 14.3 | ||
Total body irradiation | ||||||||
8-12 Gy | 14 | 6.6 | 14 | 100.0 | ||||