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Table 1 Clinical characteristics of 5-year survivors of acute lymphoblastic leukemia

From: Increased health care utilization by survivors of childhood lymphoblastic leukemia is confined to those treated with cranial or total body irradiation: a case cohort study

  ALL survivors Chemotherapy only CRT TBI
n = 213 % n = 104 % n = 95 % n = 14 %
Age at diagnosis         
  <5 yrs 111 52.1 61 58.7 45 47.4 5 35.7
  5-9 yrs 71 33.3 34 32.7 33 34.7 4 28.6
  10-17 yrs 31 14.6 9 8.7 17 17.9 5 35.7
Period of diagnosis         
  1970-1979 42 19.7 3 2.9 39 41.1 0 0
  1980-1989 78 36.6 39 37.5 32 33.7 7 50.0
  1990-1999 93 43.7 62 59.6 24 25.3 7 50.0
Age at end of follow-up         
  10-19 yrs 54 25.4 46 44.2 6 6.3 2 14.3
  20-29 yrs 71 33.3 39 37.5 26 27.4 6 42.9
  30-39 yrs 73 34.3 15 14.4 53 55.8 5 35.7
  >40 yrs 15 7.6 4 3.8 10 10.5 1 7.1
Relapse 24 11.3 2 1.9 11 11.6 11 78.6
Stem cell transplantation 14 6.6 0 0 0 0 14 100.0
Cranial irradiation         
  12-15 Gy 2 0.9    2 2.1 0 0
  18 Gy 28 13.1    28 28.4 1 7.1
  20-23 Gy 6 2.8    6 6.3 0 0
  24-30 Gy 62 29.1    60 63.2 2 14.3
Total body irradiation         
  8-12 Gy 14 6.6      14 100.0
  1. Abbreviations: ALL acute lymphoblastic leukemia, CRT received cranial irradiation in addition to chemotherapy, TBI received total body irradiation in addition to chemotherapy, including three cases who, in addition, received cranial irradiation.