Table 4 Univariate analysis of biological variables on overall survival
From: Inaugural bone metastases in non-small cell lung cancer: a specific prognostic entity?
Biological parameters | N | OS ( months) | HR | p |
|---|---|---|---|---|
Leucocytes | ||||
≥10 000/mm3 | 23 | 5.2 | 2.23 | 0.0031 |
<10 000/mm3 | 30 | 12.6 | CI 95% 1.02-4.15 | |
Neutrophils | ||||
< 8000/mm3 | 38 | 12.6 | 3.08 | 0.0001 |
≥ 8000/mm3 | 15 | 4 | CI 95% 1.36-7 | |
Lymphocytopenia | ||||
Yes | 26 | 7.6 | 1.53 | 0.11- NS |
No | 27 | 15.6 | CI 95% 0.87-2.7 | |
Hemoglobin | ||||
<11 g/dl | 9 | 6.5 | 0.39 | 0.0066 |
≥ 11 g/dl | 44 | 11 | CI 95% 0.14-1.09 | |
Albuminemia | ||||
≥ 35 g/L | 32 | 14.5 | 0.27 | 0.0001 |
<35 g/L | 10 | 5.22 | CI 95% 0.09-0.84 | |
Alkaline phosphatases | ||||
< 100 UI/L | 20 | 11.2 | 1.93 | 0.0165 |
≥ 100 UI /L | 35 | 6.4 | CI 95% 1.12-3.32 | |
Corrected calcemia | ||||
≥ 2,60 mmol/L | 11 | 5 | 2.38 | 0.008 |
< 2,60 mmol/L | 38 | 11.2 | CI 95% 0.96-5.88 | |
C-Reactive Protein | < 0.0001 | |||
≥ 7 mg/L | 35 | 6.45 | 4.3 | |
< 7 mg/L | 11 | 34 | CI 95% 2.38-7.8 |