Table 4 EORTC QLQ–C30 scales and TN stage
| Â | T* | Â | N** | Â | ||||
|---|---|---|---|---|---|---|---|---|
| Â | T1 | T2 | T3 | T4 | Â | N0 | N+ | Â |
(n = 25) | (n = 30) | (n = 24) | (n = 48) | (n = 43) | (n = 84) |  | ||
EORTC QLQ-C30 | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | p | Mean (SD) | Mean (SD) | p |
Emotional functioning | 75.6 (27.9) | 70.8 (34.1) | 53.8 (35.8) | 60.0 (33.0) | 0.085 | 69.5 (31.0) | 54.6 (36.2) | 0.039 |
Physical functioning | 90.4 (17.2) | 84.6 (17.6) | 75.2 (25.5) | 74.5 (26.1) | 0.025 | 83.8 (21.0) | 73.1 (26.1) | 0.024 |
Role functioning | 97.3 (13.3) | 79.4 (34.3) | 77.7 (36.3) | 74.3 (33.8) | 0.010 | 86.3 (27.2) | 69.7 (38.5) | 0.004 |
Cognitive functioning | 82.6 (22.8) | 85.5 (18.9) | 79.1 (28.7) | 81.2 (27.8) | 0.938 | 84.1 (24.1) | 78.2 (26.6) | 0.158 |
Social functioning | 98.6 (6.6) | 91.1 (22.6) | 83.3 (23.0) | 87.8 (29.1) | 0.035 | 94.0 (19.4) | 81.7 (29.0) | 0.002 |
Global quality of life/QoL | 75.6 (19.1) | 69.7 (26.5) | 60.7 (33.6) | 60.9 (26.4) | 0.130 | 70.3 (23.4) | 57.1 (31.6) | 0.033 |
Fatigue | 9.3 (16.8) | 15.1 (22.3) | 25.4 (30.1) | 30.5 (32.6) | 0.012 | 16.9 (26.5) | 31.2 (29.7) | 0.003 |
Nausea and Vomiting | 3.3 (10.7) | 3.3 (9.1) | 11.8 (24.8) | 4.8 (14.9) | 0.252 | 3.9 (13.1) | 8.5 (19.7) | 0.090 |
Pain | 8.0 (16.0) | 33.8 (34.3) | 45.8 (44.0) | 47.2 (38.4) | <0.001 | 27.5 (34.3) | 52.7 (39.8) | 0.001 |
Dyspnea | 5.3 (12.4) | 6.6 (22.1) | 19.4 (33.9) | 7.6 (22.0) | 0.124 | 9.1 (23.9) | 9.3 (23.3) | 0.816 |
Insomnia | 25.3 (36.3) | 32.2 (39.6) | 30.5 (43.8) | 48.6 (45.5) | 0.129 | 30.5 (39.4) | 48.8 (46.7) | 0.041 |
Appetite loss | 17.3 (33.4) | 24.4 (40.9) | 38.8 (41.3) | 39.5 (41.0) | 0.041 | 25.3 (38.5) | 43.4 (41.4) | 0.010 |
Constipation | 9.3 (29.0) | 25.5 (38,8) | 33.3 (43.9) | 25.6 (40.2) | 0.127 | 20.2 (36.2) | 31.0 (43.2) | 0.135 |
Diarrhea | 0 | 1.1 (6.0) | 5.5 (21.2) | 2.0 (10.6) | 0.511 | 0.7 (5.1) | 4.6 (18.6) | 0.199 |
Financial difficulties | 12.0 (27.0) | 24.4 (40.9) | 45.8 (48.9) | 36.8 (44.6) | 0.039 | 22.6 (38.0) | 46.5 (47.7) | 0.006 |