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Table 4 EORTC QLQ–C30 scales and TN stage

From: Influence of pain severity on the quality of life in patients with head and neck cancer before antineoplastic therapy

  T*   N**  
  T1 T2 T3 T4   N0 N+  
(n = 25) (n = 30) (n = 24) (n = 48) (n = 43) (n = 84)  
EORTC QLQ-C30 Mean (SD) Mean (SD) Mean (SD) Mean (SD) p Mean (SD) Mean (SD) p
Emotional functioning 75.6 (27.9) 70.8 (34.1) 53.8 (35.8) 60.0 (33.0) 0.085 69.5 (31.0) 54.6 (36.2) 0.039
Physical functioning 90.4 (17.2) 84.6 (17.6) 75.2 (25.5) 74.5 (26.1) 0.025 83.8 (21.0) 73.1 (26.1) 0.024
Role functioning 97.3 (13.3) 79.4 (34.3) 77.7 (36.3) 74.3 (33.8) 0.010 86.3 (27.2) 69.7 (38.5) 0.004
Cognitive functioning 82.6 (22.8) 85.5 (18.9) 79.1 (28.7) 81.2 (27.8) 0.938 84.1 (24.1) 78.2 (26.6) 0.158
Social functioning 98.6 (6.6) 91.1 (22.6) 83.3 (23.0) 87.8 (29.1) 0.035 94.0 (19.4) 81.7 (29.0) 0.002
Global quality of life/QoL 75.6 (19.1) 69.7 (26.5) 60.7 (33.6) 60.9 (26.4) 0.130 70.3 (23.4) 57.1 (31.6) 0.033
Fatigue 9.3 (16.8) 15.1 (22.3) 25.4 (30.1) 30.5 (32.6) 0.012 16.9 (26.5) 31.2 (29.7) 0.003
Nausea and Vomiting 3.3 (10.7) 3.3 (9.1) 11.8 (24.8) 4.8 (14.9) 0.252 3.9 (13.1) 8.5 (19.7) 0.090
Pain 8.0 (16.0) 33.8 (34.3) 45.8 (44.0) 47.2 (38.4) <0.001 27.5 (34.3) 52.7 (39.8) 0.001
Dyspnea 5.3 (12.4) 6.6 (22.1) 19.4 (33.9) 7.6 (22.0) 0.124 9.1 (23.9) 9.3 (23.3) 0.816
Insomnia 25.3 (36.3) 32.2 (39.6) 30.5 (43.8) 48.6 (45.5) 0.129 30.5 (39.4) 48.8 (46.7) 0.041
Appetite loss 17.3 (33.4) 24.4 (40.9) 38.8 (41.3) 39.5 (41.0) 0.041 25.3 (38.5) 43.4 (41.4) 0.010
Constipation 9.3 (29.0) 25.5 (38,8) 33.3 (43.9) 25.6 (40.2) 0.127 20.2 (36.2) 31.0 (43.2) 0.135
Diarrhea 0 1.1 (6.0) 5.5 (21.2) 2.0 (10.6) 0.511 0.7 (5.1) 4.6 (18.6) 0.199
Financial difficulties 12.0 (27.0) 24.4 (40.9) 45.8 (48.9) 36.8 (44.6) 0.039 22.6 (38.0) 46.5 (47.7) 0.006
  1. *Kruskal-Wallis test, **Mann Whitney test. Abbreviations: T, Tumor size; N, Lymph node involvement.