Figure 2
From: The effects of conjugate and light dose on photo-immunotherapy induced cytotoxicity
Sequential microscopic images of MDA-MB-468luc cells treated with Pan- IR700 (images before (left), during (middle) and after (right) irradiation, upper images; DIC images, lower images; fluorescence images). PIT induced cell death with swelling, budding and rupture of the membrane as shown on the DIC images (middle and right). Fluorescence signals decreased after continuous NIR irradiation. Scale bar: 50 μm (original magnification, ×400).