Table 3 Associations between the subcellular localization of ERα/ERβ1 and clinicopathological factors in female PTC patients
ERα | Tumor size | LNM | ETE | TNM | ||||
|---|---|---|---|---|---|---|---|---|
≤20 mm | >20 mm | + | - | + | - | I/II | III/IV | |
Reproductive age a | ||||||||
Nu (n = 28) | 16/28 (57.1%) | 12/28 (42.9%) | 15/28 (53.6%) | 13/28 (46.4%) | 10/28 (35.7%) | 18/28 (64.3%) | 25/28 (89.3%) | 3/28 (10.7%) |
Nu + Cyto/Cyto (n = 8) | 3/8 (37.5%) | 5/8 (62.5%) | 4/8 (50.0%) | 4/8 (50.0%) | 0 | 8/8 (100%) | 8/8 (100%) | 0 |
P-value | 0.908 | 0.858 | 0.047 | 0.334 | ||||
Advanced reproductive age b | ||||||||
Nu (n = 7) | 5/7 (71.4%) | 2/7 (28.6%) | 2/7 (28.6%) | 5/7 (71.4%) | 4/7 (57.1%) | 3/7 (42.9%) | 4/7 (57.1%) | 3/7 (42.9%) |
Nu + Cyto/Cyto (n = 11) | 4/11 (36.4%) | 7/11 (63.6%) | 5/11 (45.5%) | 6/11 (54.5%) | 2/11 (18.2%) | 9/11 (81.8%) | 6/11 (54.5%) | 5/11 (45.5%) |
P-value | 0.109 | 0.474 | 0.087 | 0.914 | ||||
ERβ1 | Tumor size | LNM | ETE | TNM | ||||
≤20 mm | >20 mm | + | - | + | - | I/II | III/IV | |
Reproductive age | ||||||||
Nu (n = 7) | 5/7 (71.4%) | 2/7 (28.6%) | 2/7 (28.6%) | 5/7 (71.4%) | 1/7 (14.3%) | 6/7 (85.7%) | 7/7 (100%) | 0 |
Nu + Cyto/Cyto (n = 41) | 19/41 (46.3%) | 22/41 (53.7%) | 25/41 (61.0%) | 16/41 (39.0%) | 15/41 (36.6%) | 26/41 (63.4%) | 38/41 (92.7%) | 3/41 (7.3%) |
P-value | 0.374 | 0.110 | 0.247 | 0.460 | ||||
Advanced reproductive age | ||||||||
Nu (n = 3) | 2/3 (66.7%) | 1/3 (33.3%) | 0 | 3/3 (100%) | 0 | 3/3 (100%) | 3/3 (100%) | 0 |
Nu + Cyto/Cyto(n = 36) | 14/36 (38.9%) | 22/36 (61.1%) | 16/36 (44.4%) | 20/36 (55.5%) | 16/36 (44.4%) | 20/36 (55.5%) | 16/36 (44.4%) | 20/36 (55.5%) |
P-value | 0.300 | 0.133 | 0.133 | 0.064 | ||||