Figure 2
From: The nucleolar size is associated to the methylation status of ribosomal DNA in breast carcinomas
DNA methylation of rDNA locus in pair-matched normal and tumor tissues. (A) The correlation matrices of CpG sites analyzed in the 3 target regions (RiboPromoter, 18S and 28S) are reported for normal (left panel) and tumor (right panel) tissues. (B) The methylation levels of rDNA CpG sites are reported for 45 pair-matched normal (left panel) and tumor (right panel) tissues. (C) The boxplot compares, for each CpG site included in the analysis, the DNA methylation levels in 45 normal and tumor tissues.