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Table 5 Comparison of serum concentrations of AAT in the group of patients with colorectal cancer (total and classified by TNM stages) vs. controls

From: Serum concentration of alpha-1 antitrypsin is significantly higher in colorectal cancer patients than in healthy controls

 

GP controls

CRC

TNM stage of CRC cases

 

Total

Total

I

II

III

IV

Number of subjects (%)

327 (100)

267 (100)

33 (12)

124 (47)

85 (32)

25 (9)

Mean serum AAT (SD)

138.5 (25.3)

198.1 (58.0)

197.9 (63.0)

194.3 (60.1)

198.9 (55.7)

214.5 (59.3)

 

P-value A*: <0.001

P-value B**: 0.502

    
  1. CRC colorectal carcinoma. GP general population. Serum concentration values are expressed in mg/dL. SD standard deviation.
  2. P-value A*: from the comparison of mean values of serum AAT in the control and CRC groups, and between the mean AAT in the control group and the partial AAT value for each TNM subgroup.
  3. P-value B**: from the comparison of the mean value of the whole CRC group and each CRC stage (I- IV).