Serum concentration of alpha-1 antitrypsin is significantly higher in colorectal cancer patients than in healthy controls

Table 2 PFS, allele type, mean gene frequency and prevalence in both cohorts

Sample (n)	PFS	Total alleles	Allele types (n)			PiS and PiZ mean gene frequencyin x 1,000 [95% CI]		Hardy-Weinberg calculated prevalence [1/x]
			M	S	Z	Pi*S	Pi*Z	MM	MS	MZ	SS	SZ	ZZ
General population (327)	5.4	654	581	63	10	96 [75-122]	15 [8-29]	1.3	6	37	108	339	4,267
Colorectal cancer (267)	5.4	534	473	50	11	94 [71-122]	21 [11-38]	1.3	6	27	114	259	2,357
P-value						0.954	0.639

N number, PFS precision factor score (scale 0-12), CI confidence interval, Pi* protease inhibitor. No significant differences were found in any of the comparisons.

ISSN: 1471-2407