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Figure 4 | BMC Cancer

Figure 4

From: Estrogen receptor α and aryl hydrocarbon receptor independent growth inhibitory effects of aminoflavone in breast cancer cells

Figure 4

AhR knockdown does not alter AF sensitivity in MDA-MB-468 and Cal51 . (A) GI50 (growth inhibition) mediated by AF plotted as concentration of AF in log [M] versus number of viable MDA-MB-468shAhR cells treated with vehicle control. All GI50 data is presented as a 95% confidence interval of the GI50 value for AF. (B) GI50 (growth inhibition) mediated by AF plotted as concentration of AF in log [M] versus number of viable MDA-MB-468shAhR cells treated with 750 ng/mL Dox in the tissue culture media for seven days prior to experiment plating (and maintained throughout the experiment). (C) GI50 (growth inhibition) mediated by AF plotted as concentration of AF in log [M] versus number of viable Cal51shAhR cells treated with vehicle control. (D) GI50 (growth inhibition) mediated by AF plotted as concentration of AF in log [M] versus number of viable Cal51shAhR cells treated with 750 ng/mL Dox in the tissue culture media for seven days prior to experiment plating (and maintained throughout the experiment). All cells were treated with AF for seven days.

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