Figure 4

AhR knockdown does not alter AF sensitivity in MDA-MB-468 and Cal51 . (A) GI₅₀ (growth inhibition) mediated by AF plotted as concentration of AF in log [M] versus number of viable MDA-MB-468shAhR cells treated with vehicle control. All GI₅₀ data is presented as a 95% confidence interval of the GI50 value for AF. (B) GI₅₀ (growth inhibition) mediated by AF plotted as concentration of AF in log [M] versus number of viable MDA-MB-468shAhR cells treated with 750 ng/mL Dox in the tissue culture media for seven days prior to experiment plating (and maintained throughout the experiment). (C) GI₅₀ (growth inhibition) mediated by AF plotted as concentration of AF in log [M] versus number of viable Cal51shAhR cells treated with vehicle control. (D) GI₅₀ (growth inhibition) mediated by AF plotted as concentration of AF in log [M] versus number of viable Cal51shAhR cells treated with 750 ng/mL Dox in the tissue culture media for seven days prior to experiment plating (and maintained throughout the experiment). All cells were treated with AF for seven days.