Table 1 Demographics and the distribution of IDO expression
Variable | Total N (%) | IDO expression | |
|---|---|---|---|
Mean | P-value | ||
Age, years | 121 | ||
<50 | 85 (70.2) | 7.0 | <0.001 |
≥50 | 36 (29.8) | 20.2 | |
Sex | 121 | ||
Female | 41 (33.9) | 7.4 | <0.001 |
Male | 80 (66.1) | 12.8 | |
Histologic subtype | 121 | ||
NLP | 5 (4.1) | 3.3 | <0.001 |
NS | 64 (52.9) | 5.8 | |
MC | 46 (38.0) | 19.2 | |
LD | 1 (0.8) | 15.6 | |
LR | 1 (0.8) | 1.1 | |
Unclassifiable | 4 (3.3) | 8.9 | |
Ann Arbor stage | 115 | ||
I-II | 66 (57.4) | 6.9 | 0.004 |
III-IV | 49 (42.6) | 17.3 | |
B symptoms | 107 | ||
Yes | 34 (31.8) | 16.2 | 0.454 |
No | 73 (68.2) | 9.1 | |
Bulky disease | 104 | ||
Yes | 8 (7.7) | 11.8 | 0.826 |
No | 96 (92.3) | 11.8 | |
IPS | 116 | ||
≤2 | 82 (70.7) | 7.5 | 0.013 |
>2 | 34 (29.3) | 20.6 | |
EBV status | 96 | ||
Positive | 43 (44.8) | 17.4 | 0.069 |
Negative | 53 (55.2) | 8.7 | |
HIV status | 121 | ||
Positive | 3 (2.5) | 58.6 | 0.001 |
Negative | 118 (97.5) | 9.7 | |
Treatment response | 98 | ||
Success | 65 (66.3) | 10.0 | 0.098 |
Relapse | 21 (21.4) | 11.0 | |
Progression | 12 (12.2) | 26.4 | |