Table 2 Correlation between Beclin-1 expression and clinicopathologic characteristics in HCC

Age

1.382#/0.155

<50 y

53

12

22.6

28

52.8

13

24.5

≥50 y

50

16

32

25

50

9

18

Sex

4.360#/0.175

Male

85

23

27.1

47

55.3

15

17.6

Female

18

5

27.8

6

33.3

7

38.9

AFP

−0.096/0.334

<50 ng/ml

39

8

20.5

22

56.4

9

23.1

≥50 ng/ml

64

20

31.3

31

48.4

13

20.3

HbsAg

−0.111/0.264

Negative

20

4

20

10

50

6

30

Positive

83

24

28.9

43

51.8

16

19.3

Liver cirrhosis

0.216 /0.029*

No

20

3

15

9

45

8

40

Yes

83

25

30.1

44

53

14

16.9

Tumor size

−0.035/0.726

≤2 cm

14

3

21.4

7

50.0

4

28.6

2 cm-10 cm

78

22

28.2

41

52.6

15

19.2

>10 cm

11

3

27.3

5

45.5

3

27.3

Edmondson grades

−0.249/0.011*

I-II

49

8

16.3

27

55.1

14

28.6

III-IV

54

20

37

26

48.1

8

14.8

TNM stage

0.146/0.142

I

10

2

10

4

40

4

50

II

41

7

17.1

27

71.1

7

18.4

III

36

13

30.7

16

46.2

7

23.1

IV

16

6

25

6

37.5

4

37.5

Capsule integrity

−0.054/0.588

Yes

67

16

23.9

34

50.7

17

25.4

No

36

12

33.3

19

52.8

5

13.9

Vascular invasion

−0.246/0.012*

No

70

13

18.6

40

57.1

17

24.3

Yes

33

15

45.5

13

39.4

5

15.2

Tumor number

−0.158/0.111

Single

73

17

23.6

38

52.05

18

25

Multiple

30

11

37.9

15

50.0

4

13.8