Skip to main content

Table 2 Correlation between Beclin-1 expression and clinicopathologic characteristics in HCC

From: The expression of beclin-1, an autophagic gene, in hepatocellular carcinoma associated with clinical pathological and prognostic significance

Characteristics N Beclin-1 expression R (X2# )/P
   (−) % (+) % (++) %  
Age         1.382#/0.155
<50 y 53 12 22.6 28 52.8 13 24.5  
≥50 y 50 16 32 25 50 9 18  
Sex         4.360#/0.175
Male 85 23 27.1 47 55.3 15 17.6  
Female 18 5 27.8 6 33.3 7 38.9  
AFP         −0.096/0.334
<50 ng/ml 39 8 20.5 22 56.4 9 23.1  
≥50 ng/ml 64 20 31.3 31 48.4 13 20.3  
HbsAg         −0.111/0.264
Negative 20 4 20 10 50 6 30  
Positive 83 24 28.9 43 51.8 16 19.3  
Liver cirrhosis         0.216 /0.029*
No 20 3 15 9 45 8 40  
Yes 83 25 30.1 44 53 14 16.9  
Tumor size         −0.035/0.726
≤2 cm 14 3 21.4 7 50.0 4 28.6  
2 cm-10 cm 78 22 28.2 41 52.6 15 19.2  
>10 cm 11 3 27.3 5 45.5 3 27.3  
Edmondson grades         −0.249/0.011*
I-II 49 8 16.3 27 55.1 14 28.6  
III-IV 54 20 37 26 48.1 8 14.8  
TNM stage         0.146/0.142
I 10 2 10 4 40 4 50  
II 41 7 17.1 27 71.1 7 18.4  
III 36 13 30.7 16 46.2 7 23.1  
IV 16 6 25 6 37.5 4 37.5  
Capsule integrity         −0.054/0.588
Yes 67 16 23.9 34 50.7 17 25.4  
No 36 12 33.3 19 52.8 5 13.9  
Vascular invasion         −0.246/0.012*
No 70 13 18.6 40 57.1 17 24.3  
Yes 33 15 45.5 13 39.4 5 15.2  
Tumor number         −0.158/0.111
Single 73 17 23.6 38 52.05 18 25  
Multiple 30 11 37.9 15 50.0 4 13.8  
  1. *, p<0.05.