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Table 1 Correlation of perineural invasion with patients’ clinicopathological features in primary esophageal squamous cell carcinomas

From: The prognostic effect of perineural invasion in esophageal squamous cell carcinoma

Variables

Perineural invasion

Cases

Absent

Present

P value*

Age (years)

   

0.083

  ≤ 57.0†

230

110 (47.8%)

120 (52.2%)

 

  > 57.0

203

114 (56.2%)

89 (43.8%)

 

Gender

   

0.502

  Female

112

61 (54.5%)

51 (45.5%)

 

  Male

321

163 (50.8%)

158 (49.2%)

 

Location

   

0.098

  Upper

28

14 (50.0%)

14 (50.0%)

 

  Middle

298

145 (48.7%)

153 (51.3%)

 

  Lower

107

65 (60.7%)

42 (39.3%)

 

Tumor size (cm)

   

0.952

  ≤ 4‡

277

143 (51.6%)

134 (48.4%)

 

  > 4

156

81 (51.9%)

75 (48.1%)

 

Differentiation

   

0.017

  Well

67

41 (61.2%)

26 (38.8%)

 

  Moderate

288

153 (53.1%)

135 (46.9%)

 

  Poor

78

30 (38.5%)

48 (61.5%)

 

pT status

   

0.036

  T1

20

15 (75.0%)

5 (25.0%)

 

  T2

104

59 (56.7%)

45 (43.3%)

 

  T3

309

150 (48.5%)

159 (51.5%)

 

pN status

   

< 0.0001

  N0

233

137 (58.8%)

96 (41.2%)

 

  N1

111

59 (53.2%)

52 (46.8%)

 

  N2

71

25 (35.2%)

46 (64.8%)

 

  N3

18

3 (16.7%)

15 (83.3%)

 

Stage

   

< 0.0001

  I

25

19 (76.0%)

6 (24.0%)

 

  II

238

138 (58.0%)

100 (42.0%)

 

  III

170

67 (39.4%)

103 (60.6%)

 
  1. *Chi-square test; †Median age; ‡Median size.