Figure 3From: The novel IGF-IR/Akt–dependent anticancer activities of glucosamine The inhibitory effect of glucosamine and IGF-1R targeting agents on the IGF-1R/Akt pathway. (A) The effect of knocking down IGF-1R on the pAkt level and cell growth. (B and C) Western blotting (left) and MTT assay (right) of A549 and H460 cells treated with PPP (B) and A12 (C) at the concentrations indicated. *P < 0.05 denotes significant differences between the conditions indicated.Back to article page