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Figure 1 | BMC Cancer

Figure 1

From: Systemic treatment with CAR-engineered T cells against PSCA delays subcutaneous tumor growth and prolongs survival of mice

Figure 1

Lentivirus cassette and surface expression of PSCA-CAR on T cells. (A) The design of the PSCA-CAR-encoding lentiviral vector is shown. (B) Expression of the PSCA-CAR molecule on the surface CD3+ T cells after transduction with the lentiviral vector was analyzed by flow cytometry using Alexa-647 F(ab')2 Fragment of Goat Anti-Mouse IgG (H + L). The solid filled histogram represents PSCA-CAR expression of transduced T cells, complex histogram represents CAR expression on Mock lentivirus-transduced T cells and the dashed histogram represents untransduced control T cells.

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