Table 1 Up-regulated genes in HPMCs exposed to malignant ascites versus to benign fluids (Fold change > 2, P < 0.05)

Hs.425633

CKMT1B

Creatine kinase mitochondrial 1B

Mitochondria

31.80

Hs.282409

CYP2C19

Cytochrome P450, family 2, subfamily C

Electron transport

29.10

Hs.560

APOBEC1

Apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1

mRNA processing

17.19

Hs.516922

NKX2-2

NK2 transcription factor related locus 2

Transcription

16.20

Hs.553484

ANGPT2

Angiopoietin-2A

Angiogenesis

16.16

Hs.145932

MTL5

Metallothionein-like 5

Anti-apoptotic

11.40

Hs.445098

DEPDC1

DEP domain containing 1

Intracellular signaling

7.06

Hs.149924

LILRB1

Leucocyte immunoglobulin-like receptor, subfamily B

Immune response

6.31

Hs.471494

EIF2C4

mRNA for KIAA1567

Protein synthesis

6.06

Hs.272215

KLF15

Kruppel-like factor 15

Transcription

5.74

Hs.285829

DLEU7

Deleted in lymphocytic leukemia 7

Intracellular signaling

5.23

Hs.6702

KCNB2

Potassium voltage-gated chanel

Cation transport

5.08

Hs.351403

DZIP1L

DAZ interacting protein 1-like

Ion binding

4.60

Hs.479853

EPHA5

EPH receptor A5

Intracellular signaling

4.54

Hs.122583

UTG2A3

UDP glucuronosyltransferase 2 family

Metabolism

4.23

Hs.446021

SLC37A3

Solute carrier family 37

Transport

4.02

Hs.270833

AREG

Amphiregulin

Cell proliferation

3.52

Hs.467793

FLJ40869

Hypothetical protein FLJ40869

DNA repair

3.31

Hs.441975

BIRC4BP

XIAP-associated factor 1

Ion binding

3.26

Hs.531941

MYB

myeloblastosis viral oncogene homolog

Transcription

2.83

Hs.585869

ZNF224

Zinc finger protein 224

Transcription

2.57

Hs.188518

MT1K

Metallothionein 1 K

Ion binding

2.54

Hs.190043

MOSPD2

Motile sperm domain containing 2

Membrane protein

2.52

Hs.270543

GNB4

Guanine nucleotide binding protein, beta polypeptide 4

Intracellular signaling

2.44

Hs.190622

DDX58

DEAD box polypeptide 58

DNA binding

2.37

Hs.658169

SFRP4

Secreted frizzled-related protein 4

Intracellular signaling

2.37

Hs.13852

DNAJB4

Hsp40 homolog, subfamily B, member 4

Protein folding

2.36

Hs.189920

PB1

Polybromo 1

Transcription

2.35

Hs.513044

CSPG4

Chondroitin sulfate proteoglycan 4

Cell motility

2.32

Hs.520506

FBXO5

F-box protein 5

Protein degradation

2.28

Hs.83634

HCFC1

Host cell factor C1

Cell proliferation

2.25

Hs.14794

ZFP28

Zinc finger protein 28 homolog

Transcription

2.19

Hs.10319

UGT2B7

UDP glucuronosyltransferase 2 family

Metabolism

2.17

Hs.503093

ZFP36L2

Zinc finger protein 36, C3H type-like 2

Cell proliferation

2.14

Hs.110915

IL22RA1

Interleukin 22 receptor, alpha 1

Immune response

2.13

Hs.442344

IRS2

Insulin receptor substrate 2

Cell proliferation

2.11

Hs.479670

TEC

Tec protein tyrosine kinase

Intracellular signaling

2.10

Hs.167700

SMAD5

SMAD, family member 5

Transcription

2.10

Hs.541894

ANKRD36

Ankirin repeat domain 36

Catalytic activity

2.09

Hs.655199

MT1A

Metallothionein 1A

Ion binding

2.09

Hs.407190

FKBP5

FK506 binding protein 5

Protein folding

2.06

Hs.744289

ZNF549

Zinc finger protein 549

Ion binding

2.06

Hs.431550

MAP4K4

Mitogen-activated protein kinase kinase kinase kinase 4

Intracellular signaling

2.04

Hs.433702

EIF5

Eukaryotic translation initiation factor 5

Translation

2.04

Hs.167584

SLC2A2

Solute carrier family 2

Transport

2.03

Hs.405144

SFRS3

Splicing factor, arginine/serine-rich 3

RNA binding

2.02