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Figure 6 | BMC Cancer

Figure 6

From: Hepatitis B spliced protein (HBSP) promotes the carcinogenic effects of benzo [alpha] pyrene by interacting with microsomal epoxide hydrolase and enhancing its hydrolysis activity

Figure 6

Effects of HBSP on tumorigenicity of B [alpha] P- treated Huh- 7 hepatoma cells in nude mice. BALB/c nude mice were inoculated with either the Huh-7/HBSP/B[alpha]P or Huh-7/GFP/B[alpha]P. Tumor size was measured every 3 days. All mice were sacrificed after 21 days of inoculation. (A) The resulting tumors photographed on the 21st day after inoculation. (B) The tumors dissected out from the sacrificed mice. (C) BPED-DNA in tumor tissues detected by immunohistochemistry assay. Images were taken at × 400 magnification. (D) Weights of tumors dissected out from the sacrificed mice (* P < 0.01). (E) Tumor volume during growth, results were expressed as mean ± SD.

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