Cell lines | IC50at 24 h (nM) | IC50at 48 h (nM) |
---|
HuCCT1 | 124.1 ± 21.5 | 12.6 ± 0.6 |
QBC939 | 82.2 ± 5.1 | 20.5 ± 4.2 |
FRH0201 | 54.1 ± 13.1 | 18.5 ± 0.7 |
- Cells were plated in 96-well plates and treated with indicated concentrations (0-200 nM) of triptolide for 24 and 48 h. IC50 values were calculated using a nonlinear dose–response curve fit and expressed as mean ± SEM.