Figure 1

Dicer and Drosha expression in triple negative breast cancer. A) Relative quantification of Dicer and Drosha by real-time RT-PCR in tumour (n = 35) samples. B) The correlation between Dicer and Drosha expression levels. C) Relative quantification of Dicer and Drosha by real-time RT-PCR in all NAT (n = 18) and IDC (n = 35) samples. D) Relative quantification of Dicer and Drosha by real-time RT-PCR in matched NAT (n = 18) and IDC (n = 18) samples. E) Correlation between Dicer and Drosha fold change in IDC versus NAT samples. Results are shown as the relative normalised expression (target/β2-Microglobulin) of the target (2^-ΔCt). Boxes (A) represent the median ± interquartile range. Horizontal line (C) represents the median ± interquartile range. Decreased and increased expression in tumour versus normal (D) is shown in green and red respectively. *p < 0.0001, **p = 0.0039, ***p = 0.0432, ^#p = 0.0235.