Table 1 Clinicopathological and histology characteristics of breast cancer tissue microarray samples
From: NILCO biomarkers in breast cancer from Chinese patients
Breast cancer | Non-malignant | ||||
|---|---|---|---|---|---|
Characteristic | ER- (n=21) | ER+(n=33) | TNBC (n=13) | P-value* | Hyperplasias (n=3) or Fibroadenomas (n=2) |
Age | 50.86 (± 12.47) | 48.67 (± 11.15) | 48.69 (± 11.6) | 0.778 | 34.2 (± 11.67) |
Grade | |||||
I | 0 (0) | 1 (3.03) | 0 (0) | 0.969 | NA |
II | 6 (28.57) | 10 (30.3) | 3 (23.08) | ||
III | 15 (71.43) | 22 (66.67) | 10 (76.92) | ||
Stage | |||||
1 | 1 (4.76) | 1 (3.03) | 0 (0) | 0.142 | NA |
2 | 17 (80.95) | 20 (60.61) | 5 (38.46) | ||
3 | 2 (9.52) | 7 (21.21) | 4 (30.77) | ||
4 | 1 (4.76) | 5 (15.15) | 4 (30.77) | ||
ER | |||||
Negative | 21 (100) | 0 (0) | 13 (100) | <.001 | 2 (40) |
Positive | 0 (0) | 33 (100) | 0 (0) | 3 (60) | |
PR | |||||
Negative | 19 (90.48) | 11 (33.33) | 13 (100) | <.001 | 2 (40) |
Positive | 2 (9.52) | 22 (66.67) | 0 (0) | 3 (60) | |
HER2 | |||||
Negative | 2 (9.52) | 12 (36.36) | 13 (100) | <.001 | 5 (100) |
Positive | 19 (90.48) | 21 (63.64) | 0 (0) | NA | |
EGFR | |||||
Negative | 13 (61.9) | 31 (93.94) | 8 (61.54) | 0.004 | 5 (100) |
Positive | 8 (38.1) | 2 (6.06) | 5 (38.46) | NA | |
AR | |||||
Negative | 14 (66.67) | 13 (39.39) | 13 (100) | <.001 | 3 (60) |
Positive | 7 (33.33) | 20 (60.61) | 0 (0) | 2 (40) | |
Ki67 | |||||
Negative | 8 (38.1) | 10 (30.3) | 5 (38.46) | 0.791 | 5 (100) |
Positive | 13 (61.9) | 23 (69.7) | 8 (61.54) | NA | |
P53 | |||||
Negative | 16 (76.19) | 24 (72.73) | 9 (69.23) | 0.903 | 5 (100) |
Positive | 5 (23.81) | 9 (27.27) | 4 (30.77) | NA | |