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Table 3 Multivariable analysis of cell markers and disease free survival (DFS)

From: p21 and CD166 as predictive markers of poor response and outcome after fluorouracil-based chemoradiotherapy for the patients with rectal cancer

Variables

HR (95% CI)

p-value

Tumor regression grade 1

1

0.046

Tumor regression grade 2

0.257 (0.079,0.853)

0.024

Tumor regression grade 3

0.065 (0.007,0.604)

0.016

Tumor regression grade 4*

<0.001 (NA).

0.999

ypN0

1

0.001

ypN1

9.025 (2.276,35.792)

0.002

ypN2

15.542 (3.634,66.462)

0.001

CD166

5.614 (1.816,17.356)

0.003

p21

6.146 (2.035,18.559)

0.001

  1. *No event (disease recurrence) was observed.