Figure 3

LCL85 overcomes metastatic breast cancer cell resistance to Fas-mediated apoptosis. MDA-MB-231 cells were incubated with LCL85 at the indicated doses in the absence or presence of FasL (250 ng/ml) for approximately 24 h. Cells were stained with Annexin V and PI and analyzed by flow cytometry. Cell death was indicated at the top right corner of each plot.