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Table 5 Mode of detection and subsequent breast cancer mortality in relation to breast density

From: Breast density and mode of detection in relation to breast cancer specific survival: a cohort study

  Rate of breast cancer deaths HR1 HR2 HR3 HR4
All      
 Non-symptomatic 27 of 350 1.00 1.00 1.00 1.00
 Symptomatic 49 of 269 2.68 (1.67-4.28) 1.55 (0.95-2.53) 1.52 (0.92-2.50) 1.56 (0.94-2.58)
 Freedmans%*    55.5 57.5 54.9
Fatty/moderate      
 Non-symptomatic 16 of 233 1.00 1.00 1.00
 Symptomatic 28 of 172 2.63 (1.42-4.87) 1.48 (0.76-2.88) 1.54 (0.79-3.02)
Dense      
 Non-symptomatic 11 of 117 1.00 1.00 1.00
 Symptomatic 21 of 97 2.63 (1.26-5.47) 1.71 (0.75-3.90) 1.63 (0.68-3.91)
  1. HR1: Crude.
  2. HR2: Adjusted for diagnostic age (continuous), tumour size (mm), ALNI, grade, ER, PgR and diagnostic period.
  3. HR3 Adjusted for same factors as HR2 but also for BMI at baseline (continuous), HRT at diagnosis and diagnostic period.
  4. HR4: Adjusted for the same factors as HR3 but also for breast density.
  5. *Freedmans% express to what extent covariates can explain the differences in mortality between non-symptomatic vs. symptomatic patients.