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Table 5 Mode of detection and subsequent breast cancer mortality in relation to breast density

From: Breast density and mode of detection in relation to breast cancer specific survival: a cohort study

 

Rate of breast cancer deaths

HR1

HR2

HR3

HR4

All

     

 Non-symptomatic

27 of 350

1.00

1.00

1.00

1.00

 Symptomatic

49 of 269

2.68 (1.67-4.28)

1.55 (0.95-2.53)

1.52 (0.92-2.50)

1.56 (0.94-2.58)

 Freedmans%*

  

55.5

57.5

54.9

Fatty/moderate

     

 Non-symptomatic

16 of 233

1.00

1.00

1.00

 Symptomatic

28 of 172

2.63 (1.42-4.87)

1.48 (0.76-2.88)

1.54 (0.79-3.02)

Dense

     

 Non-symptomatic

11 of 117

1.00

1.00

1.00

 Symptomatic

21 of 97

2.63 (1.26-5.47)

1.71 (0.75-3.90)

1.63 (0.68-3.91)

  1. HR1: Crude.
  2. HR2: Adjusted for diagnostic age (continuous), tumour size (mm), ALNI, grade, ER, PgR and diagnostic period.
  3. HR3 Adjusted for same factors as HR2 but also for BMI at baseline (continuous), HRT at diagnosis and diagnostic period.
  4. HR4: Adjusted for the same factors as HR3 but also for breast density.
  5. *Freedmans% express to what extent covariates can explain the differences in mortality between non-symptomatic vs. symptomatic patients.