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Table 4 Breast density and subsequent breast cancer mortality in relation to mode of detection

From: Breast density and mode of detection in relation to breast cancer specific survival: a cohort study

 

Rate of breast cancer deaths

HR1

HR2

HR3

HR4

All

     

 Fatty

7 of 93

1.00

1.00

1.00

1.00

 Moderate

37 of 312

1.82 (0.81-4.08)

1.80 (0.79-4.10)

2.02 (0.87-4.67)

2.09 (0.90-4.85)

 Dense

32 of 214

1.92 (0.85-4.35)

2.24 (0.97-5.13)

2.56 (1.07-6.11)

2.63 (1.10-6.30)

 p-value for trend

 

0.173

0.058

0.039

0.035

Non-symptomatic

     

 Fatty

3 of 50

1.00

1.00

1.00

 Moderate

13 of 183

1.37 (0.39-4.81)

1.30 (0.36-4.76)

1.40 (0.38-5.17)

 Dense

11 of 117

1.47 (0.41-5.27)

1.66 (0.43-6.41)

2.04 (0.49-8.49)

 p-value for trend

 

0.586

0.427

0.293

Symptomatic

     

 Fatty

4 of 43

1.00

1.00

1.00

 Moderate

24 of 129

2.43 (0.84-7.02)

2.20 (0.74-6.51)

2.62 (0.86-7.98)

 Dense

21 of 97

2.33 (0.80-6.80)

2.71 (0.91-8.06)

3.40 (1.06-10.90)

 p-value for trend

 

0.216

0.081

0.045

  1. HR1: Crude.
  2. HR2: Adjusted for diagnostic age (continuous), tumour size (mm), ALNI, grade, ER PgR and diagnostic period.
  3. HR3 Adjusted for same factors as HR2 but also for HRT at diagnosis, BMI at baseline (continuous) and diagnostic period.
  4. HR4: Adjusted for the same factors as HR3 but also for mode of detection (non-symptomatic or symptomatic).