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Table 4 Breast density and subsequent breast cancer mortality in relation to mode of detection

From: Breast density and mode of detection in relation to breast cancer specific survival: a cohort study

  Rate of breast cancer deaths HR1 HR2 HR3 HR4
All      
 Fatty 7 of 93 1.00 1.00 1.00 1.00
 Moderate 37 of 312 1.82 (0.81-4.08) 1.80 (0.79-4.10) 2.02 (0.87-4.67) 2.09 (0.90-4.85)
 Dense 32 of 214 1.92 (0.85-4.35) 2.24 (0.97-5.13) 2.56 (1.07-6.11) 2.63 (1.10-6.30)
 p-value for trend   0.173 0.058 0.039 0.035
Non-symptomatic      
 Fatty 3 of 50 1.00 1.00 1.00
 Moderate 13 of 183 1.37 (0.39-4.81) 1.30 (0.36-4.76) 1.40 (0.38-5.17)
 Dense 11 of 117 1.47 (0.41-5.27) 1.66 (0.43-6.41) 2.04 (0.49-8.49)
 p-value for trend   0.586 0.427 0.293
Symptomatic      
 Fatty 4 of 43 1.00 1.00 1.00
 Moderate 24 of 129 2.43 (0.84-7.02) 2.20 (0.74-6.51) 2.62 (0.86-7.98)
 Dense 21 of 97 2.33 (0.80-6.80) 2.71 (0.91-8.06) 3.40 (1.06-10.90)
 p-value for trend   0.216 0.081 0.045
  1. HR1: Crude.
  2. HR2: Adjusted for diagnostic age (continuous), tumour size (mm), ALNI, grade, ER PgR and diagnostic period.
  3. HR3 Adjusted for same factors as HR2 but also for HRT at diagnosis, BMI at baseline (continuous) and diagnostic period.
  4. HR4: Adjusted for the same factors as HR3 but also for mode of detection (non-symptomatic or symptomatic).