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Table 3 Standard incidence ratios (SIR) with 95% confidence intervals (CI) for a second malignancy by cancer site in men and women with a history of cutaneous malignant melanoma (CMM), adjusted for age and calendar period

From: New malignancies after squamous cell carcinoma and melanomas: a population-based study from Norway

   Women (N = 15 1841) Men (N = 12 9721)
ICD-10 Cancer site2 O3 SIR (95% CI) O3 SIR (95% CI)
C00-14 Mouth, pharynx 14 0.77 (0.46,1.30) 33 1.11 (0.79,1.56)
C18 Colon 163 1.02 (0.88,1.19) 134 1.16 (0.98,1.37)
C19-21 Rectum 57 0.87 (0.67,1.13) 62 0.93 (0.72,1.19)
C25 Pancreas 46 1.00 (0.76,1.33) 39 1.06 (0.77,1.45)
C33,34,38 Lung 109 1.12 (0.93,1.35) 119 0.72 (0.60,0.87)
C50 Breast 377 1.24 (1.12,1.37) - -
C50-58 Female organs 588 1.18 (1.09,1.28) - -
C61 Prostate - - 445 1.26 (1.15,1.38)
C64-68 Urinary organs 68 0.93 (0.73,1.18) 139 0.99 (0.84,1.17)
C70-72 CNS4 70 1.39 (1.09,1.75) 41 1.31 (0.98,1.78)
C73 Thyroid 19 1.27 (0.81,1.99) 13 2.78 (1.61,4.80)
C81-85 Lymphoma 56 1.29 (0.99,1.68) 60 1.56 (1.20,1.99)
C91-95 Leukemia 72 1.28 (1.01,1.60) 64 1.22 (0.87,1.43)
C00-965 Other sites 169 1.15 (0.99,1.34) 176 1.07 (0.92,1.24)
C43 CMM 438 7.59 (6.91,8.33) 411 9.44 (8.57,10.4)
C44 SCC 197 3.12 (2.71,3.59) 204 3.11 (2.71,3.56)
C00-96 All sites 2066 1.52 (1.46,1.59) 1943 1.49 (1.43,1.60)
C00-966 All, exc. skin 1431 1.16 (1.11,1.23) 1328 1.12 (1.06,1.18)
C00-967 All, exc. CMM 1628 1.26 (1.20,1.32) 1532 1.25 (1.19,1.31)
  1. 1The number of cancer cases in the SIR-analyses differs slightly from that used in the logistic regression analyses as the data were extracted on different dates from the Cancer Registry of Norway. 2The cancer sites are not mutually exclusive. 3Observed number of cases. 4Central nervous system tumors. 5Includes ICD-10 codes C15-17, C22-24, C26, C30-32, C37, C39-41, C45-49, C60, C62-63, C69, C74-76, C80, C88, C90. 6All sites except C43 and C44. 7All sites except C43.