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Table 2 Odds ratios (OR) and 95% confidence intervals (CI) from a fully saturated discrete-time logistic regression model, comparing the risk of a first cancer in the general population with that of a second cancer in skin cancer survivors

From: New malignancies after squamous cell carcinoma and melanomas: a population-based study from Norway

  CMM SCC
  Events/Pyr1 OR (95% CI) Events/Pyr OR (95% CI)
Primary skin cancer     
 No 143 978/31.0 mill 1.00 ref 144 179/31.0 mill 1.00 ref
 Yes 3662/288 823 1.53 (1.48,1.59) 5612/175 641 2.30 (2.22,2.37)
Sex     
 Female 72 768/15.8 mill 1.00 ref 72 319/15.7 mill 1.00 ref
 Male 75 206/15.4 mill 1.28 (1.26,1.29) 77 472/15.4 mill 1.31 (1.29,1.32)
Age 2     
 20-40 years 6447/12.0 mill 1.00 ref 6509/12.0 mill 1.00 ref
 40-59 years 30 795/10.6 mill 5.37 (5.22,5.52) 30 241/10.5 mill 5.28 (5.14,5.43)
 ≥ 60 years 110 732/8.6 mill 20.58 (20.04,21.14) 113 041/8.6 mill 20.34 (19.80,20.9)
Residential region 3     
 North 21 277/6.0 mill 1.00 ref 21 323/6.0 mill 1.00 ref
 Mid 34 586/7.2 mill 1.30 (1.27,1.32) 34878/7.2 mill 1.30 (1.28,1.32)
 South 92 111/18.0 mill 1.33 (1.31,1.35) 93 590/17.9 mill 1.35 (1.33,1.37)
Calendar period 2     
 < 1965 8477/4.3 mill 1.00 ref 8354/4.3 mill 1.00 ref
 1965-1974 20 484/5.4 mill 2.54 (2.47,2.61) 20 867/5.4 mill 2.62 (2.56,2.6)
 1975-1984 27 276/5.9 mill 3.63 (3.54,3.73) 27 573/5.9 mill 3.73 (3.63,3.83)
 1985-1994 33 071/6.3 mill 4.28 (4.17,4.40) 33 817/6.3 mill 4.45 (4.34,4.57)
 1995-2004 40 142/6.6 mill 5.33 (5.19,5.47) 40 241/6.6 mill 5.41 (5.27,5.56)
 ≥ 2005 18 524/2.7 mill 5.99 (5.82,6.17) 18 939/2.6 mill 6.22 (6.04,6.40)
Educational level 4     
 ≤ Primary school 15 926/1.9 mill 1.00 ref 16 141/1.9 mill 1.00 ref
 Secondary school 67 042/11.8 mill 0.32 (0.31,0.33) 67 915/11.8 mill 0.32 (0.31,0.33)
 Some college 35 646/7.0 mill 0.30 (0.29,0.31) 36 079/7.0 mill 0.30 (0.29,0.30)
 ≥ College degree 29 360/10.5 mill 0.30 (0.29,0.31) 29 656/10.4 mill 0.30 (0.30,0.31)
Marital status 3     
 Not married 47 085/15.7 mill 1.00 ref 47 881/15.7 mill 1.00 ref
 Married 100 889/15.5 mill 1.25 (1.24,1.27) 101 910/15.4 mill 1.27 (1.25,1.28)
Parental status 4     
 No children 138 424/28.9 mill 1.00 ref 139 451/28.9 mill 1.00 ref
 Children 9550/2.3 mill 0.95 (0.93,0.97) 10 340/2.2 mill 0.96 (0.94,0.98)
Income (annual) 3     
 $ 05 60 395/9.1 mill 1.00 ref 62 871/9.1 mill 1.00 ref
 $ 80–9 999 40 528/10.7 mill 0.92 (0.90,0.93) 40 556/10.7 mill 0.91 (0.90,0.92)
 $ 10 000–19 999 34 425/8.7 mill 0.80 (0.79,0.82) 34 394/8.7 mill 0.80 (0.78,0.80)
 $ 20 000–39 999 11 582/2.6 mill 0.78 (0.77,0.80) 11 140/2.5 mill 0.76 (0.74,0.78)
 $ ≥ 40 000 1044/153 034 0.82 (0.77,0.87) 830/122 013 0.78 (0.73,0.84)
  1. 1Number of events (new cancers) per person-year during follow-up. 2Time-varying covariates (yearly). 3At start of follow-up. 4At end of follow-up. 5Includes also those with missing income data.