From: The pemetrexed-containing treatments in the non-small cell lung cancer, is -/low thymidylate synthase expression better than +/high thymidylate synthase expression: a meta-analysis
Study
Median progression free survival time(months)
Median ratio
pvalue
TS +/high
TS -/low
Bepler et al. [6]
20.7
21
1.01
0.187
Chang et al. [29]
1.3
2.4
1.85
0.407
Chen et al. [21]
3.4
4.8
1.41
0.01
Sun et al. [17]
2
4.1
2.05
0.001
Igawa et al. [30]
1.6
5.8
3.63
0.03
Pool
7.6
1.31
(95% CI 0.43-2.19)
0.13
