From: The pemetrexed-containing treatments in the non-small cell lung cancer, is -/low thymidylate synthase expression better than +/high thymidylate synthase expression: a meta-analysis
Study
Median survival time(months)
Median ratio
pvalue
TS +/high
TS -/low
Bepler et al. [6]
27.8
27
0.97
0.272
Chang et al. [30]
6.7
9.5
1.42
0.688
Chen et al. [21]
10
21.4
2.14
0.09
Sun et al. [17]
18.9
22.3
1.18
0.106
Igawa et al. [31]
8.6
14.7
1.71
0.04
Pool
14.4
19.0
1.32(95% CI 0.92-2.72)
0.24
