Table 2 List of included single nucleotide polymorphisms (SNPs), and their frequencies (percentages)
Genotype | ||||||
|---|---|---|---|---|---|---|
Gene | n | GG | GA | AA | CC | CA |
n (%) | n (%) | n (%) | n (%) | n (%) | ||
ABCC2/MRP2rs8187710 | 954 | 842 (88.3) | 110 (11.5) | 2 (0.2) | ||
ABCG2/BRCPrs2231137 | 955 | 888 (93.0) | 67 (7.0) | |||
CYP2B6rs2279343 | 910 | 57 (6.2) | 382 (42.0) | 471 (51.8) | ||
CYP2C8rs72558196 | 960 | 960 (100) | ||||
CYP2C9rs1057910 | 954 | 853 (89.4) | 3 (0.3) | 98 (10.3) | ||
CYP2C19rs4244285 | 946 | 652 (68.9) | 266 (28.1) | 28 (3.0) | ||
CYP2C19rs4986893 | 960 | 960 (100) | ||||
CYP3A4rs2740574 | 955 | 2 (0.2) | 57 (6) | 896 (93.8) | ||
CYP3A4rs55785340 | 957 | 957 (100) | ||||
CYP3A5rs776746 | 959 | 834 (87.0) | 118 (12.3) | 7 (0.7) | ||
DPYDrs1801159 | 960 | 47 (4.9) | 267 (27.8) | 646 (67.3) | ||
DPYDrs3918290 | 949 | 945 (99.6) | 4 (0.4) | |||
DPYDrs1801160 | 957 | 853 (89.1) | 96 (10.0) | 8 (0.9) | ||
GSTA1rs3957357 | 938 | 329 (35.1) | 441 (47.0) | 168 (17.9) | ||
GSTP1rs1695 | 959 | 118 (12.3) | 452 (47.1) | 389 (40.6) | ||
MRP1rs1883112 | 956 | 295 (30.9) | 485 (50.7) | 176 (18.4) | ||
MRP1rs7853758 | 952 | 701 (73.6) | 231 (24.3) | 20 (2.1) | ||
MTHFRrs1801131 | 951 | 446 (46.9) | 92 (9.7) | 413 (43.4) | ||
UGT2B7rs12233719 | 949 | 949 (100) | ||||
UGT2B7rs7662029 | 955 | 210 (22.0) | 473 (49.5) | 272 (28.5) | ||
XPD/ERCC2rs1799793 | 954 | 412 (43.2) | 429 (45.0) | 113 (11.8) | ||
XRCC1rs25489 | 954 | 875 (91.7) | 77 (8.1) | 2 (0.2) | ||
XRCC3rs861534 | 949 | 357 (37.6) | 441 (46.5) | 151 (15.9) | ||
Gene | n | TT | CC | CT | AA | TA |
n (%) | n (%) | n (%) | n (%) | n (%) | ||
ABCC2/MRP2rs17222723 | 951 | 843 (88.6) | 2 (0.2) | 106 (11.2) | ||
ABCC2/MRP2rs2804402 | 935 | 297 (31.8) | 185 (19.8) | 453 (48.4) | ||
CYP2B6rs8192709 | 927 | 846 (91.3) | 87 (8.7) | |||
CYP2C8rs10509681 | 960 | 740 (77.1) | 12 (1.2) | 208 (21.7) | ||
CYP2C9rs1799853 | 957 | 15 (1.6) | 712 (74.4) | 230 (24) | ||
CYP3A4rs4986910 | 959 | 938 (97.8) | 21 (2.2) | |||
DPYDrs1801265 | 960 | 635 (66.1) | 46 (4.8) | 279 (29.1) | ||
FGFR4rs351855 | 954 | 88 (9.2) | 461 (48.3) | 405 (42.5) | ||
GSTP1rs1138272 | 952 | 6 (0.6) | 778 (81.7) | 168 (17.7) | ||
MDRI/ABCB1rs1045642 | 914 | 265 (29.0) | 208 (22.8) | 441 (48.2) | ||
MRP1rs13058338 | 949 | 482 (50.8) | 67 (7.1) | 400 (42.1) | ||
MRP1rs246221 | 956 | 462 (48.3) | 71 (7.4) | 423 (44.3) | ||
MRP1rs3743527 | 930 | 13 (1.4) | 562 (60.4) | 355 (38.2) | ||
MRP1rs4673 | 954 | 115 (12.0) | 406 (42.6) | 433 (45.4) | ||
MTHFRrs1801133 | 959 | 121 (12.6) | 401 (41.8) | 437 (45.6) | ||
NQO1rs1800566 | 958 | 35 (3.6) | 605 (63.2) | 318 (33.2) | ||
UGT2B7rs7439366 | 955 | 272 (28.5) | 210 (22.0) | 473 (49.5) | ||
UGT2B7rs7668282 | 954 | 940 (98.5) | 1 (0.1) | 13 (1.4) | ||
Gene | n | GG | GT | TT | CC | CG |
n (%) | n (%) | n (%) | n (%) | n (%) | ||
ALDH3A1rs2228100 | 934 | 67 (7.2) | 554 (59.3) | 313 (33.5) | ||
CYP2B6rs3745274 | 954 | 535 (56.1) | 365 (38.2) | 54 (5.7) | ||
GPX4rs757229 | 940 | 263 (28.0) | 212 (22.5) | 465 (49.5) | ||
MRP1rs4148350 | 957 | 847 (88.5) | 105 (11.0) | 5 (0.5) | ||
MRP1rs45511401 | 960 | 847 (88.2) | 109 (11.4) | 4 (0.4) | ||
UGT2B7rs3924194 | 954 | 19 (2.0%) | 712 (74.6) | 223 (23.4) | ||
XPD/ERCC2rs13181 | 951 | 116 (12.2) | 449 (47.2) | 386 (40.6) | ||
Gene | n | GG | GT | TT | GA | TA |
n (%) | n (%) | n (%) | n (%) | n (%) | ||
MDRI/ABCB1rs2032582 | 948 | 283 (29.9) | 445 (46.9) | 185 (19.5) | 23 (2.4) | 12 (1.3) |
TYMSrs11280056 | 918 | AAGTTA 442 (48.2) | AAGTTA.DEL 394 (42.9) | DEL 82 (8.9) | ||