Table 2 SF50 values to olaparib and the PTEN status in endometrial cancer cell lines
PTEN | Cell lines | SF50 (nM) | Mean | SE | SD | P value (Student t test) |
|---|---|---|---|---|---|---|
Mutation | HEC-265 | 8 | 746 | 253 | 838 | 0.26 |
HEC-251 | 15 | |||||
Ishikawa | 42 | |||||
HEC-88 | 170 | |||||
RL95-2 | 190 | |||||
HEC-151 | 230 | |||||
AN3CA | 400 | |||||
HHUA | 400 | |||||
HEC-6 | 1500 | |||||
HEC-116 | 1600 | |||||
HEC-59 | 1900 | |||||
HEC-108 | 2500 | |||||
Wild type | KLE | 100 | 215 | 49 | 85 | |
HEC-180 | 200 | |||||
HEC-50B | 220 | |||||
HEC-1B | 340 | |||||
Expression (+) | HEC-265 | 8 | 809 | 305 | 915 | 0.27 |
Ishikawa | 42 | |||||
RL95-2 | 190 | |||||
HEC-1B | 340 | |||||
AN3CA | 400 | |||||
HHUA | 400 | |||||
HEC-6 | 1500 | |||||
HEC-59 | 1900 | |||||
HEC-108 | 2500 | |||||
Expression (-) | HEC-251 | 15 | 362 | 208 | 551 | |
KLE | 100 | |||||
HEC-50 | 220 | |||||
HEC-180 | 200 | |||||
HEC-88 | 170 | |||||
HEC-151 | 230 | |||||
HEC-116 | 1600 |