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Table 5 Site to site gene expression comparisons from the tissue reproducibility study

From: Analytical validation of the PAM50-based Prosigna Breast Cancer Prognostic Gene Signature Assay and nCounter Analysis System using formalin-fixed paraffin-embedded breast tumor specimens

Comparison

Pairwise (n)

Intercept

Slope

Pearson

 

[95% CI]

[95% CI]

[95% CI]

All Sites

121

0.00

0.98

0.98

[-0.01–0.01]

[0.97–0.99]

[0.98–0.98]

Site 1 vs. Site 2

40

0.00

0.97

0.98

[-0.01–0.01]

[0.95–0.98]

[0.97–0.98]

Site 1 vs. Site 3

40

0.01

1.00

0.98

[0–0.02]

[0.98–1.01]

[0.98–0.99]

Site 2 vs. Site 3

41

-0.01

0.99

0.99

[-0.02–0]

[0.97–1]

[0.98–0.99]

  1. Pairwise correlations, slopes, and intercepts of normalized 50 genes for tissues replicates from the tissue reproducibility study. The average intercept, slope, and Pearson’s correlation of the pair-wise comparisons are reported with their 95% confidence intervals.
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BMC Cancer

ISSN: 1471-2407

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