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Table 4 Multivariate analysis of factors associated with overall survival in patients who underwent potentially curative resection for colorectal cancer liver metastases stratified for patients’ MSKCC clinical risk score

From: Adjuvant therapy after resection of colorectal liver metastases: the predictive value of the MSKCC clinical risk score in the era of modern chemotherapy

Variable Comparison Hazard ratio 95% CI PValue
MSKCC clinical risk score ≤ 2
Age - 1.01 0.99 – 1.04 0.20
Distribution of metastasis Bilobar vs. unilobar 1.80 1.12 – 2.92 0.01
Initial stage of disease (UICC)     0.41
1 Reference   
2 1.96 0.80 – 4.81 0.13
3 1.92 0.80 – 4.59 0.14
4 1.52 0.60 – 3.83 0.36
Adjuvant chemotherapy Adjuvant CTx vs. no adjuvant CTx 0.90 0.57 – 1.43 0.67
MSKCC clinical risk score > 2
Age - 1.00 0.98 – 1.03 0.61
Distribution of metastasis Bilobar vs. unilobar 1.65 0.98 – 2.77 0.06
Initial stage of disease (UICC)     0.21
1 Reference   
2 0.21 0.02 – 2.27 0.20
3 0.60 0.07 – 4.79 0.63
4 0.38 0.05 – 3.03 0.36
Adjuvant chemotherapy Adjuvant CTx vs. no adjuvant CTx 0.40 0.23 – 0.70 0.001
  1. CTx, Chemotherapy.
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BMC Cancer

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