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Table 1 Disease association analysis of predicted NKX3.1 targeted genes within the human genome reveals the enrichment of chromosome aberrations, inversion, breakage gene ontology categories

From: Loss of the NKX3.1 tumorsuppressor promotes the TMPRSS2-ERG fusion gene expression in prostate cancer

MeSH Disease/input n = 464

 

Genes

 

P-value

Expected

Observed

Chromosome inversion

1.67e-04

120

152

Chromosome aberration

2.06e-04

13

27

Angelman Syndrome

2.99e-04

3

10

Chromosome breakage

3.45e-04

20

36

Uniparental disomy

3.95e-04

4

12

Prader-Willi Syndrome

8.64e-04

5

13

Translocation, genetic

9.83e-04

59

82

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BMC Cancer

ISSN: 1471-2407

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