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Table 1 The frequency of PAX8- and PAX5-positive brain tumours

From: Increased paired box transcription factor 8 has a survival function in Glioma

Tumours type

n

PAX8-positive

PAX5-positive

Glioblastoma: ALT

18

8 (44%)†

0

Glioblastoma: NDTMM

56

41 (73%)*

5 (9%)

Glioblastoma: telomerase

46

37 (80%)**

2 (5%)

Astrocytoma grade I

20

1 (5%)

0

Astrocytoma grade II

6

1 (17%)

0

Astrocytoma grade III

10

4 (40%)

0

Meningioma grade I

20

1 (5%)

0

Atypical Meningioma (Grade II)

6

0

-

Malignant Meningioma (Grade III)

4

4 (100%)

0

  1. ALT, alternative lengthening of telomeres; NDTMM, non-defined telomere maintenance mechanism. †, four positive tumours showed faint immunostaining; *P < 0.05 and **P < 0.01 compared with ALT-positive tumours; -, not tested.