Table 2 The risk of association of smoking exposures during pregnancy with RAS status, NQO1 and MLL rearrangements, EAL cases, in a case-case analysis Brazil, 2000-2010
RAS wt n (%) | RAS mut n (%) | OR (95% CI) | NQO1 wtn (%) | NOQ1609CT an (%) | OR (95% CI) | MLL wt n (%) | MLL r n (%) | OR (95% CI) | |
|---|---|---|---|---|---|---|---|---|---|
Mother ever smoked | |||||||||
No | 55 (65.5) | 24 (60.0) | 1b | 39 (57.4) | 40 (71.4) | 1b | 45 (76.3) | 30 (52.6) | 1b |
Yes | 29 (34.5) | 16 (40.0) | 1.26 (0.58-2.75) | 29 (42.6) | 16 (28.6) | 0.54 (0.25-1.14) | 14 (23.7) | 27 (47.4) | 2.89 (1.31-6.40) |
Mother smoked 3 months before pregnancy | |||||||||
No | 59 (70.2) | 28 (70.0) | 1b | 44 (64.7) | 43 (76.8) | 1b | 48 (81.4) | 34 (59.6) | 1b |
Yes | 25 (29.8) | 12 (30.0) | 1.01 (0.44-2.30) | 24 (35.3) | 13 (23.2) | 0.55 (0.25-1.23) | 11 (18.6) | 23 (40.4) | 2.95 (1.27-6.85) |
Mother smoked during pregnancy | |||||||||
No | 67 (79.8) | 31 (77.5) | 1b | 52 (76.5) | 46 (82.1) | 1b | 52 (88.1) | 41 (71.9) | 1b |
Yes | 17 (20.2) | 9 (22.5) | 1.14 (0.46-2.85) | 16 (23.5) | 10 (17.9) | 0.71 (0.29-1.71) | 7 (11.9) | 16 (28.1) | 2.90 (1.09-7.71) |
Someone in the house ever smoked c | |||||||||
No | 46 (59.0) | 16 (42.1) | 1b | 38 (62.3) | 24 (43.6) | 1b | 30 (53.6) | 29 (53.7) | 1b |
Yes | 32 (41.0) | 22 (57.9) | 1.98 (0.90-4.34) | 23 (37.7) | 31 (56.4) | 2.13 (1.02-4.49) | 23 (46.4) | 25 (46.3) | 1.00 (0.47-2.11) |