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Table 1 Clinical and tumor-related characteristics of the study population (N = 244)

From: Plasma level of LDL-cholesterol at diagnosis is a predictor factor of breast tumor progression

Characteristics   No. of patients %1
Patient characteristics    
    Age (Years), mean±SD (range) 58,2±13,3 (29-91)   
    Weight (Kg), median (interquartile range) 67 (60-76)   
    Height (cm), median (interquartile range) 160 (154-163)   
    BMI (Kg/m 2 ), median (interquartile range) 26,7 (23,5-30,44)   
    Menopausal status (yes)   126 65,6
    Gestation (yes)   182 90,54
    Breast-feeding (yes)   146 79,3
    Oral contraception/HT (yes)   96 55,6
    Family history of BC♯ (yes)   56 27,5
    TC (mg/dL), median (interquartile range) 209,5 (191-231)   
    HDL-C (mg/dL), median (interquartile range) 53 (46-60)   
    LDL-C (mg/dL), median (interquartile range) 128 (110-153)   
    Triglycerides (mg/dL), median (interquartile range) 94 (74,5-126)   
Tumor characteristics 2    
    Histological type IDC 244 100
    Tumor size (mm), median (interquartile range) 21 (14-30)   
    Tumor stage (T) T1, ≤ 2 cm 122 50
  T2, 2-5 cm 115 47,2
  T3, >5 cm 7 2,8
    Tumor differentiation grade G1 27 12,4
  G2 134 61,5
  G3 57 26,2
    Immunohistochemical subtypes ER/PR positive 204 83,9
  Triple negative 23 9,5
  HER 2 Type 16 6,6
    LVI positive   61 29,2
    Nodal stage (N) N0 137 56,9
  N1, 1-3 LN+ 72 29,9
  N2, 4-9 LN+ 18 7,47
  N3, ≥10 LN+ 14 5,8
    Clinical stage I 84 34,4
  II 125 51,3
  III 35 14,3
    Bilaterality (yes)   10 4,1
  1. ¹Frequency of known cases.
  2. 2Tumor characteristics based on The American Joint Committee on Cancer [58].
  3. Histological type of breast cancer (IDC is presently named invasive carcinoma, NOS); Tumor Stage T of TNM Classification (T1≤2cm; T2:2-5cm; T3>5 cm); Tumor Differentiation Grade of Nothingham Histologic Score (G1, G2, G3); Immunohistochemical subtypes [Luminal A and B (ER/PR positive); Triple negative (ER/PR negative and Her2-neu negative); HER2 Type (ER/PR negative and Her2-neu positive)]; Pathological axillar Nodal Stage of TNM Classification (N0: no metastatic LN; N1: 1-3 metastatic LN; N2:4-9 metastatic lymph nodes; N3≥10 metastatic lymph nodes); Clinical Stage or Prognostic Stages Groups of American Joint Committee on Cancer (I, II, III,IV).
  4. HT: Hormonal Therapy; BC: Breast Cancer; BMI: Body Mass Index; HT: Hormonal Therapy; TC: Total Cholesterol; LDL-C: Low Density Lipoprotein; HDL-C: High Density Lipoprotein IDC: Invasive Ductal Carcinoma; ER: Estrogen Receptor; PR: Progesterone Receptor; LVI: Lymphovascular Invasion; LN: Lymph Nodes.