Table 1 The risk associations between ARID5B rs10821936 genotype and MLL translocation partner genes or MLL breakpoint region, Brazil, 2003-2013
Controls | MLLtranslocation partner genes | MLLbreakpoint regiona | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
MLL-AFF1(n = 44) | MLL-MLLT1(n = 21) | MLL-MLLT3(n = 17) | A (n = 15) and B (n = 8) | C (n = 18) | |||||||
n | n | OR (95% CI)b,c | n | OR (95% CI)b,c | n | OR (95% CI)b,c | n | OR (95% CI)b,c | n | OR (95% CI)b,c | |
ARID5B | |||||||||||
rs10821936 | |||||||||||
TT | 200 | 11 | 1.00 | 6 | 1.00 | 2 | 1.00 | 2 | 1.00 | 5 | 1.00 |
TC | 205 | 27 | 3.26 (1.42-7.49) | 11 | 2.82 (0.89-8.93) | 12 | 8.62 (1.77-41.94) | 17 | 12.76 (2.66-61.23) | 12 | 3.45 (1.08-11.05) |
CC | 68 | 6 | 1.95 (0.62-6.11) | 4 | 2.12 (0.52-8.63) | 3 | 5.18 (0.79-34.02) | 4 | 6.65 (1.08-41.15) | 1 | 0.85 (0.09-8.25) |
TC + CC | 273 | 33 | 2.79 (1.27-6.11) | 15 | 2.53 (0.89-7.22) | 15 | 7.10 (1.54-32.68) | 22 | 10.25 (2.24-46.81) | 14 | 2.72 (0.88-8.43) |