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Table 6 Intracellular expression of chemokine receptors after xenotransplantation

From: Intracellular coexpression of CXC- and CC– chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantation

  CXCR3 CXCR4 CXCR7 CCR7 CCR10
  % MFI % MFI % MFI % MFI % MFI
WM-115 88.59 5.40 92.45 3.95 4.97 1.57 20.16 1.70 13.67 1.57
WM-115-X 59.84 3.46 14.10 1.62 58.89 4.14 75.32 4.10 66.90 3.47
WM-115-CX 76.11 3.95 12.14 1.65 5.44 1.34 82.03 3.44 81.90 3.44
WM-266 74.08 2.22 96.26 3.39 21.53 1.68 40.16 1.69 24.00 1.63
WM-266-X 28.19 2.24 6.71 1.26 13.96 2.08 56.31 2.50 28.54 1.83
WM-266-CX 91.65 4.41 94.17 3.74 53.67 2.34 72.95 2.48 88.62 4.60
  1. Mean percentage (%) and Mean fluorescence index (MFI; calculated as the ratio between the mean fluorescence of samples stained with the mAb anti-receptor and correspondent isotypic control) of cells which significantly expressed (p < 0.05) chemokine receptors intracellularly. WM-115 and WM-266 represent the mean values of the original cell lines; WM-115-X and WM-266-X represent the mean values of the different xenografts; WM-115-CX and WM-266-CX represent the mean values of the different cell lines obtained after culturing the xenografts.