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Table 6 Intracellular expression of chemokine receptors after xenotransplantation

From: Intracellular coexpression of CXC- and CC– chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantation

 

CXCR3

CXCR4

CXCR7

CCR7

CCR10

 

%

MFI

%

MFI

%

MFI

%

MFI

%

MFI

WM-115

88.59

5.40

92.45

3.95

4.97

1.57

20.16

1.70

13.67

1.57

WM-115-X

59.84

3.46

14.10

1.62

58.89

4.14

75.32

4.10

66.90

3.47

WM-115-CX

76.11

3.95

12.14

1.65

5.44

1.34

82.03

3.44

81.90

3.44

WM-266

74.08

2.22

96.26

3.39

21.53

1.68

40.16

1.69

24.00

1.63

WM-266-X

28.19

2.24

6.71

1.26

13.96

2.08

56.31

2.50

28.54

1.83

WM-266-CX

91.65

4.41

94.17

3.74

53.67

2.34

72.95

2.48

88.62

4.60

  1. Mean percentage (%) and Mean fluorescence index (MFI; calculated as the ratio between the mean fluorescence of samples stained with the mAb anti-receptor and correspondent isotypic control) of cells which significantly expressed (p < 0.05) chemokine receptors intracellularly. WM-115 and WM-266 represent the mean values of the original cell lines; WM-115-X and WM-266-X represent the mean values of the different xenografts; WM-115-CX and WM-266-CX represent the mean values of the different cell lines obtained after culturing the xenografts.
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BMC Cancer

ISSN: 1471-2407

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