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Table 2 Toxicity profile between patients groups

From: The role of LDH serum levels in predicting global outcome in HCC patients treated with sorafenib: implications for clinical management

Clinical variables LDH LDH LDH LDH Total
≤407 U/l >407 U/l Decreased Increased
Patients 53 (%) 25 (%) 26 52 78
Any grade toxicity Global 24 (45) 9 (36) 13 (50) 20 (38) 33
Rash 5 (9) 3 (12) 4 (15) 4 (8) 8
Hand-foot 9 (17) 4 (16) 7 (27) 6 (12) 13
Nausea/vomiting 3 (6) 2 (8) 1 (4) 4 (8) 5
Diarrhea 11 (21) 3 (12) 6 (23) 8 (15) 14
Fatigue 5 (9) 5 (20) 4 (15) 6 (12) 10
Liver dysfunction 0 (0) 2 (8) 1 (4) 1 (2) 2