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Table 2 Univariate and multivariate analyses of individual parameters for correlations with overall survival rate: Cox proportional hazards model

From: miR-372 down-regulates the oncogene ATAD2 to influence hepatocellular carcinoma proliferation and metastasis

Variables Univariate Multivariate
HR CI (95%) P value HR CI (95%) P value
ATAD2 1.843 1.220-2.784 0.004a 2.221 1.444-3.416 0.001a
Age 1.253 0.856-1.542 0.407    
Gender 1.176 0.601-1.583 0.921    
Tumor stage 1.122 0.920-1.367 0.255    
HBsAg 1.150 0.792-1.670 0.464    
Tumor differentiation 1.028 0.784-1.347 0.843    
Metastasis 1.816 1.232-2.678 0.003a 1.822 1.221-2.718 0.003a
Tumor size 1.573 1.059-2.336 0.025a 1.909 1.276-2.855 0.002a
Serum AFP 1.670 1.110-2.512 0.014a 1.992 1.306-3.038 0.001a
Liver cirrhosis 1.056 0.640-1.429 0.827    
  1. Abbreviation: HR, Hazard Ratio; CI, Confidence Interval.
  2. a.Statistically significant (p < 0.05).