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Table 3 Sensitivity analysis for the relationship between intake n-3/n-6 PUFAs ratio and breast cancer risk

From: Ratio of n-3/n-6 PUFAs and risk of breast cancer: a meta-analysis of 274135 adult females from 11 independent prospective studies

Sensitivity analysis Diet ratio of n-3/n-6 Serum PL ratio of n-3/n-6 Intake ratio of n-3/n-6
N Pooled RR (95% CI) Heterogeneity N Pooled RR(95% CI) Heterogeneity N Pooled RR(95% CI) Heterogeneity
  I 2 Degree P I 2 Degree P I 2 Degree P
Exclusion of studies with potential selection bias [20, 32] 5 0.87 (0.80, 0.96) 0.00% (Low) 0.5s9 4 0.73 (0.51, 1.01) 0.00% (Low) 0.67 9 0.86 (0.79, 0.94) 0.00% (Low) 0.72
Exclusion of studies without covariates adjusted [18] 6 0.90 (0.82, 0.99) 17.30% (Low) 0.30 4 0.82 (0.56, 1.22) 36.50% (Low) 0.17 10 0.89 (0.81, 0.99) 19.10% (Low) 0.26
Contour-enhanced funnel plots of fixed effect model 6 0.91 (0.84, 0.98) 17.30% (Low) 0.30 5 0.90 (0.68, 1.19) 21.50% (Low) 0.27 11 0.91 (0.84, 0.98) 11.40% (Low) 0.33
Contour-enhanced funnel plots of random effect model 6 0.90 (0.82, 0.99) 17.30% (Low) 0.30 5 0.87 (0.63, 1.20) 21.50% (Low) 0.27 11 0.90 (0.82, 0.98) 11.40% (Low) 0.33
  1. N = number of studies; P = P value for heterogeneity within subgroup.