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Table 3 Associations between expression a of microdomain-forming proteins and clinicopathological characteristics of NSCLC patients

From: Simultaneous expression of flotillin-1, flotillin-2, stomatin and caveolin-1 in non-small cell lung cancer and soft tissue sarcomas

  Stomatin Flotillin-1 Flotillin-2 Caveolin-1
  up equal down up equal down up equal down equal down
Stomatin            
up 4           
equal   4          
down    33         
p            
Flotillin-1          
up 3 0 12 18        
equal 1 1 4   10       
down 0 2 14    17      
p 0,242         
Flotillin-2       
up 3 2 15 11 7 5 24     
equal 0 2 9 4 2 5   13    
down 0 0 6 1 1 5    8   
p 0,39 0,176      
Caveolin-1            
equal 1 1 6 5 3 1 4 6 1 12  
down 3 3 26 13 6 16 19 7 7   36
p 0,925 0,155 0,107   
Tumor size            
T1-T2 4 1 20 12 7 10 12 11 5 11 20
T3-T4 0 3 13 6 3 7 12 2 3 1 16
p 0,094 0,816 0,117 0,036 b
Lymph node status            
N0 3 4 12 7 3 9 9 8 1 5 15
N+ 1 0 21 11 7 8 15 5 7 7 21
p 0,026 c 0,476 0,078 1
Clinical stage            
I-II 3 2 18 10 4 11 11 9 3 8 18
III-IV 1 2 15 8 6 6 13 4 5 4 18
p 0,714 0,459 0,277 0,505
Degree of differentiation            
moderate 3 4 22 10 8 11 17 11 2 10 22
low 1 0 11 8 2 6 7 2 7 2 14
p 0,377 0,432 0,007 c 0,289
  1. aup – higher gene expression in tumors compared with normal tissue samples.
  2. down – lower gene expression in tumors compared with normal tissue samples.
  3. equal – no significant difference in gene expression in tumors versus normal tissue samples.
  4. bFisher’s exact test.
  5. cχ2 test.
  6. Data in bold represents statistically significant values.