Figure 5

siRNA silencing of Stat6 abolishes inhibition of T47D cell proliferation by progesterone but not by rosiglitazone. T47D cells, treated with or without progesterone (A) (30 nM) or rosiglitazone (B) (0.5 μM) and transfected with control or Stat6 siRNAs (500 ng), were harvested at 1, 2, or 3 days for measurement of DNA content. ns, not significant; *, P ≤ 0.05; **, P ≤0.01; ***, P ≤ 0.001 versus control.