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Table 1 Comparison of clinicopathological parameters in cases with or without ALK fusion

From: Allelotypes of lung adenocarcinomas featuring ALK fusion demonstrate fewer onco- and suppressor gene changes

  with fusion without fusion P
n 35 95  
Age (years) 58.5 62.8 0.050
gender    
   male 14 47 0.337
   female 21 48  
smoking    
   never 25 41 0.004
   ever 10 54  
pStage    
   I 20 60 0.532
   II-IV 15 35  
differentiation grade    
   wel 4 44 <0.001
   mod+por 31 51  
Predominant subtype    
   papillary 21 77 0.019
   Acinar 13 13  
   Bronchioloalveolar 0 4  
   solid with mucin 0 1  
   signet 1 0  
lymphatic invasion    
   - 24 68 0.738
   + 11 27  
Vessel invasion    
   - 15 51 0.273
   + 20 44  
TP53 mutation    
   - 34 75 0.014
   + 1 20  
EGFR mutation    
   - 35 40 <0.0001
   + 0 55  
KRAS mutation    
   - 35 88 0.189
   + 0 7