| |
Univariate
|
Multivariate
|
|---|
| |
HR (95% CI)
|
Pvalue
|
HR (95% CI)
|
Pvalue
|
|---|
|
Sex (male)
|
0.842 (0.604–1.173)
|
0.309
| | |
|
Age > 60 (years)
|
0.777 (0.586–1.031)
|
0.080
| | |
|
Cause (viral)
|
0.978 (0.652–1.469)
|
0.916
| | |
|
ALT > 40 (IU/L)
|
1.511 (1.146–1.992)
|
0.003
|
1.333 (0.985–1.804)
|
0.062
|
|
Child-Pugh class
|
1.803 (1.480–2.198)
|
< 0.001
|
1.711 (1.377–2.125)
|
< 0.001
|
|
Tumor size > 5 (cm)
|
3.548 (2.622–4.801)
|
< 0.001
|
1.778 (1.209–2.615)
|
0.003
|
|
Tumor multiplicity (≥ 2)
|
2.023 (1.510–2.711)
|
< 0.001
|
1.391 (1.023–1.892)
|
0.035
|
|
Presence of PVT
|
4.197 (3.141–5.609)
|
< 0.001
|
1.827 (1.284–2.598)
|
0.001
|
|
Presence of metastasis
|
3.002 (2.178–4.139)
|
< 0.001
|
1.242 (0.868–1.779)
|
0.236
|
|
AFP > 200 (ng/mL)
|
2.783 (2.099–3.690)
|
< 0.001
|
1.734 (1.248–2.407)
|
0.001
|
|
CRP > 6.3 (mg/L)
|
3.923 (2.929–5.255)
|
< 0.001
|
1.519 (1.049–2.199)
|
0.027
|
|
NLR > 2.3
|
3.050 (2.223–4.185)
|
< 0.001
|
1.601 (1.124–2.280)
|
0.009
|
-
HR, hazard ratio; CI, confidence interval; ALT, alanine aminotransferase; PVT, portal vein thrombosis; AFP, α-fetoprotein; CRP, C-reactive protein; NLR, neutrophil-to-lymphocyte ratio.
