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Table 3 CRS and HIPEC

From: A prospective multicenter phase II study evaluating multimodality treatment of patients with peritoneal carcinomatosis arising from appendiceal and colorectal cancer: the COMBATAC trial

Author, year

Pat. [n]

Cytostatic agents (HIPEC)

Median OS [mths]

Median PFS [mths]

OS [%]

Survival CC-0/1 [%]

Pilati, 2003 [66]

34

MMC/DDP

18

-

31 (2-y)

-

Glehen, 2004 [67]

53

MMC

13

-

32 (2-y)

54 (2-y)

Glehen, 2004 [63]

506

MMC/LOHP

19

-

39 (3-y)

47 (3-y)

Shen, 2004 [68]

77

MMC

16

-

25 (3-y)

44 (3-y)

Verwaal, 03/08 [59, 60]

105

MMC

22

12.6

28 (3-y)

45 (5-y)

Quenet, ASCO 08 [69]

37

LOHP/IRI

37

13

-

58 (3-y)

Elias, 2009 [46]

48

LOHP

63

-

-

51 (5-y)

Hompes, 2012 [65]

48

LOHP

-

19.8

-

89 (2y)