Grade of PRO in toxicity
|
Entity
|
---|
|
CRC
|
Non-CRC
|
u-GI
|
NSCLC
|
SCCHN
|
---|
Stomatitis
|
n= 57
|
n= 75
|
n=45
|
n=18
|
n=12
|
None
|
35.1%
|
61.3%
|
66.7%
|
66.7%
|
33.4%
|
Grade 1/2
|
54.4%
|
32.0%
|
31.1%
|
27.8%
|
41.6%
|
Grade 3/4
|
10.5%
|
6.7%
|
2.2%
|
5.5%
|
25.0%
|
Nausea
|
n=54
|
n=70
|
n=44
|
n=14
|
n=12
|
None
|
44.4%
|
21.4%
|
18.2%
|
21.5%
|
33.4%
|
Grade 1/2
|
50.0%
|
68.6%
|
72.8%
|
71.4%
|
50.0%
|
Grade 3/4
|
5.6%
|
10.0%
|
9.0%
|
7.1%
|
16.6%
|
Emesis
|
n=54
|
n=74
|
n=42
|
n=18
|
n=13
|
None
|
81.4%
|
75.7%
|
76.2%
|
72.3%
|
77.0%
|
Grade 1/2
|
16.7%
|
24.3%
|
23.8%
|
27.7%
|
23.0%
|
Grade 3/4
|
1.9%
|
0.0%
|
0.0%
|
0.0%
|
0.0%
|
Diarrhea
|
n=56
|
n=74
|
n=44
|
n=17
|
n=13
|
None
|
35.7%
|
62.1%
|
54.6%
|
76.5%
|
69.3%
|
Grade 1/2
|
50.0%
|
33.8%
|
38.6%
|
23.5%
|
30.7%
|
Grade 3/4
|
14.3%
|
4.1%
|
6.8%
|
0.0%
|
0.0%
|
Fatigue
|
n=57
|
n=76
|
n=45
|
n=18
|
n=13
|
None
|
7.0%
|
6.6%
|
6.7%
|
5.6%
|
7.7%
|
Grade 1/2
|
87.7%
|
81.6%
|
75.6%
|
94.4%
|
84.6%
|
Grade 3/4
|
5.3%
|
11.8%
|
17.7%
|
0.0%
|
7.7%
|
Sens
.
Neu
.
|
n=55
|
n=74
|
n=44
|
n=17
|
n=13
|
None
|
40.0%
|
36.5%
|
31.9%
|
41.2%
|
46.1%
|
Grade 1/2
|
65.4%
|
56.7%
|
59.1%
|
58.8%
|
46.1%
|
Grade 3/4
|
3.6%
|
6.8%
|
9.0%
|
0.0%
|
7.8%
|
Skin toxicity
|
n=58
|
n=75
|
n=45
|
n=17
|
n=13
|
None
|
57.0%
|
64.0%
|
73.4%
|
64.8%
|
30.8%
|
Grade 1/2
|
27.5%
|
25.4%
|
24.4%
|
11.7%
|
46.1%
|
Grade 3/4
|
15.5%
|
10.6%
|
2.2%
|
23.5%
|
23.0%
|
Alopecia
|
n=56
|
n=73
|
n=45
|
n=16
|
n=12
|
None
|
33.9%
|
24.6%
|
26.7%
|
18.75%
|
25.0%
|
Grade1
|
53.6%
|
56.2%
|
60.0%
|
50.0%
|
50.0%
|
Grade 2
|
12.5%
|
19.2%
|
13.3%
|
31.25%
|
25.0%
|
- Sens. Neu. = Sensory Neuropathy.