From: Epigenetic modulation of the drug resistance genes MGMT, ABCB1 and ABCG2 in glioblastoma multiforme
Characteristic | Age [Years] | Â |
---|---|---|
Median age at diagnosis | 61.6 | Â |
Range [Min.-Max.] | 40.2 - 79.9 | Â |
Patients with temozolomide therapy | Â | Â |
 Median age at diagnosis | 59.2 |  |
Patients without temozolomide therapy | Â | Â |
 Median age at diagnosis | 64.0 |  |
Characteristic | Number of patients | % of patients |
Age classes | Â | Â |
 <50 years | 11 | 17.2 |
 50 - 60 years | 18 | 28.1 |
 60 - 70 years | 20 | 31.3 |
 >70 years | 15 | 23.4 |
Sex | Â | Â |
 Male | 39 | 60.9 |
 Female | 25 | 39.1 |
Pathohistology | Â | Â |
 Glioblastoma multiforme | 64 |  |
 Relapses of primary glioblastoma multiforme | 17 |  |
Therapy | Â | Â |
 Only Radiotherapy | 11 | 17.2 |
 Radiotherapy and temozolomide | 45 | 70.3 |
 No adjuvant therapy | 6 | 9.4 |
 No therapy data applicable | 2 | 3.1 |
Overall survival (OS) | Â | Â |
 Median [Days] | 459 |  |
 Range [Min.-Max.] | 34 - 1954 |  |
 1-year survival | 38 | 59.4 |
 2-year survival | 9 | 14.1 |
OS of patients with temozolomide therapy | Â | Â |
 Median [Days] | 515 | |
 Range [Min.-Max.] | 95 - 1954 | |
OS of patients without temozolomide therapy | Â | |
 Median [Days] | 87 | |
 Range [Min.-Max.] | 34 - 701 | |
Vital status at study end (30.06.2009) | Â | Â |
 Dead | 47 | 73.4 |
 Alive | 17 | 26.6 |