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Table 3 Concordance of test results in routine diagnostic HER2 assays in breast cancer

From: Assessment of HER2 status in breast cancer: overall positivity rate and accuracy by fluorescence in situ hybridization and immunohistochemistry in a single institution over 12 years: a quality control study

 

IHC

   

FISH

0

1+

2+

3+

Non amplified

361

567

384

29

(> 99%)

(> 99%)

(95%)

(16%)

Amplified

3

3

20

155

(< 1%)

(< 1%)

(5%)

(84%)

Total (n = 1522 )

364

570

404

184

(100%)

(100%)

(100%)

(100%)

  1. Immunohistochemistry (IHC) and FISH in 2011 and 2012.
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BMC Cancer

ISSN: 1471-2407

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